BRIM Biotechnology - BRIM

Bringing transformational treatments
to patients sooner

Applying integrated and efficient translational science to develop new treatments that help combat and cure diseases.

Our Pipelines

Our extensive experience and unique drug development engine enable us to identify and incubate high-potential novel drug candidates and rapidly deliver partner-ready clinical assets. Our lead technology platform is our proprietary Pigment Epithelium-Derived Factor (PEDF) derived Short Peptide (PDSP), which can be applied across multiple therapy areas and indications. PDSP is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functions. This platform opens up exciting possibilities for wound healing and tissue regeneration due to its ability to enhance cell proliferation.

In 2015, BRIM was granted an exclusive, worldwide license for developing PDSP in all therapeutic indications including dry eye syndrome, corneal wound healing, diabetic ulcer wound healing, osteoarthritis, androgenic alopecia, and muscle/tendon regeneration.

Our lead asset, BRM421, is on track to become a first-in-class treatment for dry eye syndrome (DES) which treats and repairs cornea damage. BRM421 has demonstrated safety and efficacy in two clinical studies. BRIM is devoted to the development of other novel synthetic peptides, including treatments for severe corneal damage (BRM423), and osteoarthritis (BRM521).

Awards

2018
Drug R&D Awards

「Silver Prize In Drug Development」

This Award was given by the Taiwan Ministry of Health and Welfare and the Ministry of Economic Affairs. It is the only biotechnology related award from governmental service. This Award recognizes that BRIM421 for Dry Eye Disease is a first-in-class new drug that is effective in corneal repairing.

2019
Prominent Enterprise Awards

「Outstanding Fundraising Award」

The Taipei Prominent Enterprise Awards were designed to recognize and encourage outstanding enterprise achievements in innovation, competitiveness, market power, influence on the overall industry, economy and society, and impact on social responsibility.

2020
Taiwan BIO Awards

「Outstanding Potential Award」
Drug/Cell Therapeutic Area

BRIM’s professional expertise in translational sciences, virtual business model, and ability to develop new drugs were recognized by this award as one of the five most outstanding potential biotech companies.

2020
Taipei Biotech Awards

「Innovative Technology Award – First Prize」

The Taipei Biotech Awards encourage further investment in the field of biotech research and development. BRIM’s PDSP technology platform was the first prize winner of the “Innovative Technology Award.”

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About BRIM