BRIM Biotechnology | Product Pipeline | Novel Drug Development

Product Pipeline

Our platform

Our unique PDSP technology platform accelerates drug development.

BRIM accelerates drug development from preclinical to clinical proof of concept, targeting novel therapies for diseases with high unmet medical needs. Our projects are based on our proprietary Pigment Epithelium-Derived Factor (PEDF) derived Short Peptide (PDSP) technology platform, which can be applied across multiple therapy areas and indications.

Novel therapies

Novel therapies for diseases with high unmet medical needs.

Our lead asset, BRM421, is on track to become a first-in-class treatment for Dry Eye Syndrome (DES) which treats and repairs corneal damage. BRM421 is currently in Phase II/III clinical trials. We are also developing new drugs to treat severe corneal damage (BRM423) and osteoarthritis (BRM521), both of which are developed from our PDSP technology platform.

PRE-CLINICAL Phase 1 Phase 2 Phase 3 Dry Eye Syndrome MOA: Regeneration BRM 421 Severe Cornea Damage MOA: Regeneration BRM 423 Neurotrophic Keratitis(NK) MOA: Regeneration BRM 424 Osteoarthritis MOA: Regeneration BRM 521